BDBM365337 6-amino-5-[5-[5 (benzoylamino)-1-benzothien- 2-yl]nicotinate::US10633373, Example 42::US10669265, Example 42::US9868726, Example 42

SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3ccccc3)ccc2s1

InChI Key InChIKey=QMJKEYITGFHQIL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 365337   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365337(6-amino-5-[5-[5 (benzoylamino)-1-benzothien- 2-yl]...)
Affinity DataIC50:  503nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365337(6-amino-5-[5-[5 (benzoylamino)-1-benzothien- 2-yl]...)
Affinity DataIC50:  224nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365337(6-amino-5-[5-[5 (benzoylamino)-1-benzothien- 2-yl]...)
Affinity DataIC50:  224nMAssay Description:VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent